Dsg2 Polyclonal Antibody, 100ul DNA Synthesis Induction by IFN-gamma is enhanced

Induction by IFN-gamma is enhanced by TNF-alpha in monocytes| dermal fibroblasts and endothelial cells| and by IL-1 in astrocytes

Allelic variants of this gene are associated with microcephaly

This encoded protein is known as the D subunit and is found ubiquitously

a potent vasodilator and inhibitor of platelet aggregation

Gene Ontology (GO) annotations related to this gene include nucleic acid binding and transcription factor activity

Dsg2 Polyclonal Antibody, 100ul DNA Synthesis Induction by IFN-gamma is enhancedDSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium binding transmembrane glycoprotein components of desmosomes, cell cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18.