Hrs Polyclonal Antibody, 20ul[BT-AP04216] Cell Biology Related pseudogenes have been identified

Related pseudogenes have been identified on chromosomes 3 and 7

ALK/NPM1 (chromosome 5)

HSD3B7 encodes an enzyme (hydroxy-delta-5-steroid dehydrogenase

Mutations in this gene result in Bietti crystalline corneoretinal dystrophy

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Hrs Polyclonal Antibody, 20ul[BT-AP04216] Cell Biology Related pseudogenes have been identifiedThe protein encoded by HGS (hepatocyte growth factor regulated tyrosine kinase substrate) regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome dependent degradation.