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Atm Polyclonal Antibody, 100ul[BT-AP00725] Centrifuge Tube (Bottle) Multiple transcript variants encoding different

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Atm Polyclonal Antibody, 100ul[BT-AP00725] Centrifuge Tube (Bottle) Multiple transcript variants encoding differentThe protein encoded by ATM belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell

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Description

Multiple transcript variants encoding different isoforms have been reported| but the full-length nature and/or biological validity of some variants have not been determined

The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids

an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells

The protein encoded by BDKRB1 (bradykinin receptor B1) is one of these receptors and is synthesized de novo following tissue injury

The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene

Atm Polyclonal Antibody, 100ul[BT-AP00725] Centrifuge Tube (Bottle) Multiple transcript variants encoding differentThe protein encoded by ATM belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell

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