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S5A2 Polyclonal Antibody, 20ul Metabolic enzymes The C-terminus of the channel

SKU: 3760670409

4.8
SEK111.00 SEK146.00

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S5A2 Polyclonal Antibody, 20ul Metabolic enzymes The C-terminus of the channelThis gene encodes a microsomal protein expressed at high levels in androgen sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4 azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).

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Description

The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting

The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole

Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation

ANAPC5 encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C)

Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation

S5A2 Polyclonal Antibody, 20ul Metabolic enzymes The C-terminus of the channelThis gene encodes a microsomal protein expressed at high levels in androgen sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4 azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).

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