LIR-7 Polyclonal Antibody, 20ul[BT-AP05032] Primary Antibodies Defects in this gene are

Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2)

Cytokine receptor common subunit beta encoded by CSF2RB is the common beta chain of the high affinity receptor for IL-3

It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells

Mutations in this gene have been associated with Laron syndrome

in a three-way gene translocation in a Burkitt lymphoma cell line

LIR-7 Polyclonal Antibody, 20ul[BT-AP05032] Primary Antibodies Defects in this gene areLILRA2 encodes a member of a family of immunoreceptors that are expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. Leukocyte immunoglobulin like receptor subfamily A member 2 is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses innate immune response. Alternatively spliced transcript variants encoding different isoforms have been