TNF-IP 8 Polyclonal Antibody, 50ul DNA/RNA Isolation & Purification Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding four distinct isoforms have been reported

The protein encoded by EDA (ectodysplasin A) is a type II membrane protein that can be cleaved by furin to produce a secreted form

It is an orphan receptor

cell signaling survival

Through its disintegrin-like domain| this protein specifically interacts with the integrin beta chain| beta 3

TNF-IP 8 Polyclonal Antibody, 50ul DNA/RNA Isolation & Purification Several alternatively spliced transcript variantsTNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include cysteine type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of this gene is TNFAIP8L2. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF mediated apoptosis by inhibiting caspase 8 activity but not the processing of procaspase 8,