GCKR Polyclonal Antibody, 100ul Low retention tips the encoded protein binds to

the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex

Can also oxidize N(1)-acetylspermidine to putrescine

Overexpression of this gene in mammalian cells conferred a transformed phenotype

and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level

one protein-coding and the other not

GCKR Polyclonal Antibody, 100ul Low retention tips the encoded protein binds toGCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity onset diabetes of the young (MODY).