Shc(Phospho Tyr427) Polyclonal Antibody, 20ul Biomatrix Each MCT appears to have

Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics

Histone deacetylase 4 encoded by HDAC4 belongs to class II of the histone deacetylase/acuc/apha family

It is an adaptor protein localized in the nucleus

which are small GTPases involved in protein transport

Mutations in this gene may be associated with atrial fibrillation

Shc(Phospho Tyr427) Polyclonal Antibody, 20ul Biomatrix Each MCT appears to haveThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.