IGFBP3(Phospho Ser183) Polyclonal Antibody, 50ul Syringe Filter and the skeletal muscle isoform

and the skeletal muscle isoform is encoded by PHKA1 (phosphorylase kinase regulatory subunit alpha 1)

This gene is located in the Prader-Willi syndrome region on chromosome 15

In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two

Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction

They seem to be equally abundant

IGFBP3(Phospho Ser183) Polyclonal Antibody, 50ul Syringe Filter and the skeletal muscle isoformThis gene is a member of the insulin like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type I domain. The protein forms a ternary complex with insulin like growth factor acid labile subunit (IGFALS) and either insulin like growth factor (IGF) I or II. In this form it circulates in the plasma prolonging the half life of IGFs and altering their interaction with cell surface receptors.