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TOB1 Polyclonal Antibody, 50ul Peripheral Blood Separation Tube subunit:Homopolymer

SKU: 29922700252

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TOB1 Polyclonal Antibody, 50ul Peripheral Blood Separation Tube subunit:HomopolymerTOB1 encodes a member of the transducer of erbB 2 B cell translocation gene protein family. Members of this family are anti proliferative factors that have the potential to regulate cell growth. The transducer of ERBB2, 2 may function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

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Description

subunit:Homopolymer

It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells

Mutations in this gene are associated with xeroderma pigmentosum complementation group A

Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin-protein transferase activity

Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBXO18/FBH1 and BLM

TOB1 Polyclonal Antibody, 50ul Peripheral Blood Separation Tube subunit:HomopolymerTOB1 encodes a member of the transducer of erbB 2 B cell translocation gene protein family. Members of this family are anti proliferative factors that have the potential to regulate cell growth. The transducer of ERBB2, 2 may function as a tumor suppressor. Alternate splicing results in multiple transcript variants.

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