NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation MC5R encodes a member of

MC5R encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction

Rac GTPase activating protein 1 plays a regulatory role in cytokinesis

The protein encoded by this gene interacts with several other proteins

and stress-induced genes

is a E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage

NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation MC5R encodes a member ofProtein numb homolog encoded by NUMB plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome dependent manner by MDM2, is a membrane bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.