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SRPK1 Polyclonal Antibody, 50ul Cell Screening and Imaging F2RL3 is activated by thrombin

SKU: 2833697576

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SRPK1 Polyclonal Antibody, 50ul Cell Screening and Imaging F2RL3 is activated by thrombinSRPK1 (SRSF protein kinase 1) encodes a serine arginine protein kinase specific for the SR (serine arginine rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of SRPK1 results in multiple transcript variants. Additional alternatively

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Description

F2RL3 is activated by thrombin and trypsin

in which it interacts directly with SKP1

This gene has been identified in some studies as a candidate gene for asthma

This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in KRT2 have been associated with bullous congenital ichthyosiform erythroderma

Mice lacking this gene exhibit early embryonic death

SRPK1 Polyclonal Antibody, 50ul Cell Screening and Imaging F2RL3 is activated by thrombinSRPK1 (SRSF protein kinase 1) encodes a serine arginine protein kinase specific for the SR (serine arginine rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of SRPK1 results in multiple transcript variants. Additional alternatively

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