4E-BP1 Monoclonal Antibody, 100ul[BT-MCA0091] Mechanical Pipette An increase in apoC-III levels

An increase in apoC-III levels induces the development of hypertriglyceridemia

This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes

The encoded protein may also play a role in

AMPH encodes a protein (amphiphysin) associated with the cytoplasmic surface of synaptic vesicles

Germinal center kinases (GCKs)

4E-BP1 Monoclonal Antibody, 100ul[BT-MCA0091] Mechanical Pipette An increase in apoC-III levelsThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV