TLE1 Rabbit Polyclonal Antibody, 20ul Immunology Polymorphisms in this gene may

Polymorphisms in this gene may be associated with type 2 diabetes

and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD)

This gene is involved in epidermal differentiation| and it is expressed at high levels in normal and psoriatic skin| but not in cultured keratinocytes or in any other tested cell types or tissues

Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4

which suggested a role in hair development

TLE1 Rabbit Polyclonal Antibody, 20ul Immunology Polymorphisms in this gene may