DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 50ul Protein Modification The enzyme has steroid 18-hydroxylase

The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity

|tissue specificity:Skeletal muscle| liver| heart and kidney

which can cause excessive production of reactive oxygen species and cell stress

This subunit binds to core promoter sequences encompassing the transcription start site

protein sorting

DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 50ul Protein Modification The enzyme has steroid 18-hydroxylaseThe protein encoded by this gene is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4