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PLB Polyclonal Antibody, 100ul Immunology when complexed to CAK

SKU: 24059296016

4.1
PLN123.75 PLN173.75

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PLB Polyclonal Antibody, 100ul Immunology when complexed to CAKThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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Description

when complexed to CAK

The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini

and it therefore likely functions in spermatid formation

disease:Chromosomal aberrations involving FOXO1 are a cause of rhabdomyosarcoma 2 (RMS2)

Pseudogenes of this gene have been defined on chromosomes 14 and 17

PLB Polyclonal Antibody, 100ul Immunology when complexed to CAKThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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