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CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette Acts as a costimulatory signal

SKU: 22102413783

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CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette Acts as a costimulatory signalCRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.

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Description

Acts as a costimulatory signal for T-cell proliferation and cytokine secretion

and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion

Activated by diacylglycerol (DAG) (By similarity)

Disruption of this gene has been implicated in Carpenter syndrome as well as cancer

Alpha-1B-glycoprotein encoded by A1BG is a plasma glycoprotein of unknown function

CD6 Polyclonal Antibody, 50ul[BT-AP02235] Digital Burette Acts as a costimulatory signalCRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS dependent fashion. It is a substrate of the BCR ABL tyrosine kinase, plays a role in fibroblast transformation by BCR ABL, and may be oncogenic.

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