NLK Polyclonal Antibody, 20ul Drying & Desiccation ATG10 is an E2-like enzyme

ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A

Essential for spermatogonia formation

Mutations in VIM causes a dominant

The encoded protein is involved in cell adhesion and cell communication in numerous cell types

Three transcript variants encoding different isoforms have been found for CD83

NLK Polyclonal Antibody, 20ul Drying & Desiccation ATG10 is an E2-like enzymeCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by tyrosine and threonine phosphorylation (By similarity). Activated by activin.,Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt beta catenin signaling pathway and the phosphorylation and destruction of the MYB