ANO5 Rabbit Polyclonal Antibody, 50ul ADME Also expressed in certain liver

Also expressed in certain liver and kidney carcinomas

which may play a role in the signal transduction pathway mediated by multiple Wnt proteins

The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region

May act as a downstream effector of CDC42 in cytoskeletal reorganization

May exert this function by promoting GLI1 nuclear localization

ANO5 Rabbit Polyclonal Antibody, 50ul ADME Also expressed in certain liverThis gene encodes a member of the anoctamin family of transmembrane proteins. The encoded protein is likely a calcium activated chloride channel. Mutations in this gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described.