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p57(Phospho Thr310) Polyclonal Antibody, 100ul Aspirating Pipets This protein may contribute to

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p57(Phospho Thr310) Polyclonal Antibody, 100ul Aspirating Pipets This protein may contribute toThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes

The protein encoded by CDKL3 (cyclin dependent kinase like 3) is a member of cyclin-dependent protein kinase (CDK) family

In addition| protein levels decrease in the presence of natural killer lytic-associated molecule| suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis

Seems to prevent the degeneration of motor axons after axotomy

p57(Phospho Thr310) Polyclonal Antibody, 100ul Aspirating Pipets This protein may contribute toThis gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

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