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CROCC Polyclonal Antibody, 50ul Vortex Mixer The CCR4-NOT complex plays a

SKU: 20167935789

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CROCC Polyclonal Antibody, 50ul Vortex Mixer The CCR4-NOT complex plays aMajor structural component of the ciliary rootlet, a cytoskeletal like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Contributes to centrosome cohesion before mitosis.,PTM: Phosphorylated by NEK2 which may regulate its association with centrosomes. Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the rootletin family.,subcellular

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Description

The CCR4-NOT complex plays a role in many cellular processes| including miRNA-mediated repression| mRNA degradation| and transcriptional regulation

EMR4P may represent a transcribed pseudogene

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains

setting in motion a cascade of downstream signals

an extragenic suppressor of the heat-sensitive bimD6 mutation that fails to attach properly to the spindle microtubules at a restrictive temperature

CROCC Polyclonal Antibody, 50ul Vortex Mixer The CCR4-NOT complex plays aMajor structural component of the ciliary rootlet, a cytoskeletal like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Contributes to centrosome cohesion before mitosis.,PTM: Phosphorylated by NEK2 which may regulate its association with centrosomes. Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the rootletin family.,subcellular

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