PRR12 Rabbit Polyclonal Antibody, 20ul Microplate Mixer leucine zipper (bZIP) transcription factor

leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD

The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns

A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation

This peptide may also play a role in mood disorders

The cytogenetic location of this locus has been reported as both 8p11 and 8q11

PRR12 Rabbit Polyclonal Antibody, 20ul Microplate Mixer leucine zipper (bZIP) transcription factorThis gene encodes a proline rich protein that contains two A T hook DNA binding domains. A chromosomal translocation and gene fusion between this gene and zinc finger MIZ type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient. Enriched expression of this gene in embryonic mouse brain suggests that this gene may play a role in nervous system development.