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p53AIP1 Polyclonal Antibody, 100ul PCR Series The protein encoded by this

SKU: 15440643095

4.8
EUR141.00 EUR175.00

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p53AIP1 Polyclonal Antibody, 100ul PCR Series The protein encoded by thisTP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1) is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of TP53AIP1 is inducible by p53, and it is thought to play an important role in mediating p53 dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for TP53AIP1.

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Description

The protein encoded by this gene contains seven ankyrin repeats

It contains a PR-domain and multiple zinc finger motifs

A mutation in the serine-rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610)

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins

as well as bradykinin and kallidin

p53AIP1 Polyclonal Antibody, 100ul PCR Series The protein encoded by thisTP53AIP1 (tumor protein p53 regulated apoptosis inducing protein 1) is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of TP53AIP1 is inducible by p53, and it is thought to play an important role in mediating p53 dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for TP53AIP1.

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