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p53 Polyclonal Antibody, 50ul[BT-AP06821] Cryogenic Vials Unlike most ribosomal proteins

SKU: 15340282525

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p53 Polyclonal Antibody, 50ul[BT-AP06821] Cryogenic Vials Unlike most ribosomal proteinsTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

Unlike most ribosomal proteins

which is found mainly in the cytoplasm

The amino-terminal region is protease resistant and globular in shape

and with Senior-Loken syndrome type 4

but it has been mapped to 4q

p53 Polyclonal Antibody, 50ul[BT-AP06821] Cryogenic Vials Unlike most ribosomal proteinsTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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