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ErbB-3 Polyclonal Antibody, 50ul[BT-AP03040] Isothermal Amplification NF-κB1 (p105/p50)

SKU: 149108506

4.4
USD185.00 USD224.00

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ErbB-3 Polyclonal Antibody, 50ul[BT-AP03040] Isothermal Amplification NF-κB1 (p105/p50)ERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

NF-κB1 (p105/p50)

Deficiency in this protein (B-cell linker)has also been shown in some cases of pre-B acute lymphoblastic leukemia

Belongs to the CAS family

MOB kinase activator 3C encoded by MOB3C is similar to the yeast Mob1 protein

Location-regulated scaffolding protein connecting MEK to RAF

ErbB-3 Polyclonal Antibody, 50ul[BT-AP03040] Isothermal Amplification NF-κB1 (p105/p50)ERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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