Phospho-Caspase-8 (S347) Polyclonal Antibody, 50ul Fluorescent Staining This gene is found to

This gene is found to be mutated in a type 2 diabetes family

see MIM 114085

subcellular location:Localizes at endoplasmic reticulum exit sites

The encoded protein plays a role in coordinating microtubule attachment by promoting recruitment of dynein proteins

SNX4 (sorting nexin 4) encodes a member of the sorting nexin family

Phospho-Caspase-8 (S347) Polyclonal Antibody, 50ul Fluorescent Staining This gene is found toCASP8 (caspase 8) encodes a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the